Recombinant Human DOT1L Protein, GST-tagged
| Cat.No. : | DOT1L-130H |
| Product Overview : | Recombinant N-terminal GST-tagged human DOT1L protein (2-416) was expressed in E. coli. |
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| Description : | The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. |
| Source : | E. coli |
| Species : | Human |
| Tag : | GST |
| Molecular Mass : | 74.1 kDa |
| Protein length : | 2-416 |
| Purity : | ≥95% as determined by SDS-PAGE |
| Stability : | ≥ 1 year |
| Storage : | At -80 centigrade. |
| Gene Name | DOT1L DOT1 like histone lysine methyltransferase [ Homo sapiens (human) ] |
| Official Symbol | DOT1L |
| Synonyms | DOT1L; DOT1 like histone lysine methyltransferase; DOT1; KMT4; histone-lysine N-methyltransferase, H3 lysine-79 specific; DOT1 like histone H3K79 methyltransferase; DOT1-like histone methyltransferase; DOT1-like protein; DOT1-like, histone H3 methyltransferase; H3-K79-HMTase; histone H3-K79 methyltransferase; histone methyltransferase DOT1L; lysine N-methyltransferase 4; EC 2.1.1.360 |
| Gene ID | 84444 |
| mRNA Refseq | NM_032482 |
| Protein Refseq | NP_115871 |
| MIM | 607375 |
| UniProt ID | Q8TEK3 |
Not For Human Consumption!
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