Recombinant Human DOCK2 Protein (Ile390-Glu635), His tagged

• Cat.No.: DOCK2-1981H
• Product Overview: Recombinant human DOCK2 (Ile390-Glu635) fused with His tag was expressed in E. coli.

Specification

• Description: Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 28.7 kDa
• Protein length: Ile390-Glu635
• Purity: >90% as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: DOCK2 dedicator of cytokinesis 2 [ Homo sapiens (human) ]
• Official Symbol: DOCK2
• Synonyms: DOCK2; dedicator of cytokinesis 2; dedicator of cyto kinesis 2; dedicator of cytokinesis protein 2; KIAA0209; dedicator of cyto-kinesis 2; FLJ46592
• Gene ID: 1794
• mRNA Refseq: NM_004946
• Protein Refseq: NP_004937
• MIM: 603122
• UniProt ID: Q92608