Recombinant Human DNAJC2 Protein, MYC/DDK-tagged

• Cat.No.: DNAJC2-2388H
• Product Overview: Recombinant Human DNAJC2 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 65.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 [ Homo sapiens ]
• Official Symbol: DNAJC2
• Synonyms: MPHOSPH11; MPP11; ZRF1; ZUO1
• Gene ID: 27000
• mRNA Refseq: NM_001129887
• Protein Refseq: NP_001123359
• MIM: 605502
• UniProt ID: Q99543