DNAJC2
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Official Full Name
DnaJ (Hsp40) homolog, subfamily C, member 2 -
Overview
M-phase phosphoprotein 11 is a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. MPP11 is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chape -
Synonyms
DNAJC2;DnaJ (Hsp40) homolog, subfamily C, member 2;ZRF1, zuotin related factor 1;dnaJ homolog subfamily C member 2;MPHOSPH11;MPP11;ZUO1;zuotin;zuotin related factor 1;zuotin-related factor 1;M-phase phosphoprotein 11;ZRF1
Recombinant Proteins
- Zebrafish
- Rhesus macaque
- Rat
- Human
- Chicken
- Cynomolgus
- Mouse
- Mammalian Cells
- E.coli
- HEK293
- His
- T7
- Avi
- Fc
- DDK
- Myc
Involved Pathway
DNAJC2 involved in several pathways and played different roles in them. We selected most pathways DNAJC2 participated on our site, such as Cellular response to heat stress,Cellular responses to stress,Regulation of HSF1-mediated heat shock response, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNAJC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of HSF1-mediated heat shock response | DNAJC7,HSPA13,DNAJB6,RPS19BP1,HSPA7,ST13,C11orf73,KIAA1967,HSPA12B,BAG5 |
| Cellular response to heat stress | BAG5,HSPA13,HSBP1,HSPA12B,MAPKAPK2B,HSBP1B,KIAA1967,HSPH1,NUPL2,NUP35 |
| Cellular responses to stress | CABIN1,TERF2IP,HIST1H1B,TERF2,ST13,HIRA,RNF2,EHMT2,PRDX3,ATG4A |
Protein Function
DNAJC2 has several biochemical functions, for example, DNA binding,Hsp70 protein binding,chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNAJC2 itself. We selected most functions DNAJC2 had, and list some proteins which have the same functions with DNAJC2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | TCEANC,MYO18A,MEOX2B,KDM2BA,H2AFVB,RBPJB,DLX5A,ZNF461,HMX4,MYPOP |
| ubiquitin binding | UBE2NB,DYRK2,PER2,C36E6.2,SQSTM1,RNF31,UBXN1,OTUB1,IWS1,TRIM32 |
| poly(A) RNA binding | AGO3,VCP,HSPD1,DAZAP1,IMP3,MRPL11,TCERG1,SRSF5,SMC1A,RPL30 |
| Hsp70 protein binding | PPID,ST13,MVD,DNAJC10,PACRG,BAG6,GPR37,CDKN1B,L7RN6,DNAJB2 |
| chromatin binding | UBE2T,SKOR2,PRKAA1,RING1,YBX1,TRPS1,MEOX1,HDAC5,RAN,SFPQ |
| histone binding | WDTC1,HIST1H3H,HIST1H3F,USP49,HIST2H3C,HIST1H3A,HIST1H4I,CTSL2,HIST1H4N,USP16 |
Interacting Protein
DNAJC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNAJC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DNAJC2.
SGTB;Hspa14
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