Recombinant Human DNAJC19, GST-tagged

• Cat.No.: DNAJC19-12079H
• Product Overview: Recombinant Human DNAJC19 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-116a.a.
• Description: The protein encoded by this gene is thought to be part of a complex involved in the ATP-dependent transport of transit peptide-containing proteins from the inner cell membrane to the mitochondrial matrix. Defects in this gene are a cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA). Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 2, 6, 10, 14 and 19.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19 [ Homo sapiens ]
• Official Symbol: DNAJC19
• Synonyms: DNAJC19; DnaJ (Hsp40) homolog, subfamily C, member 19; mitochondrial import inner membrane translocase subunit TIM14; Pam18; Tim14; TIMM14; homolog of yeast TIM14; PAM18; TIM14; FLJ99060
• Gene ID: 131118
• mRNA Refseq: NM_001190233
• Protein Refseq: NP_001177162
• MIM: 608977
• UniProt ID: Q96DA6
• Chromosome Location: 3q26.33
• Pathway: Metabolism of proteins, organism-specific biosystem; Mitochondrial Protein Import, organism-specific biosystem
• Function: heat shock protein binding