Recombinant Human DLL1, FLAG-tagged

• Cat.No.: DLL1-26670TH
• Product Overview: Recombinant fragment corresponding to amino acids 1-545 of Human DLL1 with a C terminal DDDDK tag; MWt 70 kDa .

Specification

• Species: Human
• Source: HEK293
• Tag: Flag
• Protein Length: 545 amino acids
• Description: DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family.It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication.
• Conjugation: FLAG
• Molecular Weight: 70.000kDa inclusive of tags
• Tissue specificity: Expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney.
• Biological activity: Inhibits adipogenesis of mesenchymal stem cells.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: PBS
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequence Similarities: Contains 1 DSL domain.Contains 8 EGF-like domains.

Gene Information

• Gene Name: DLL1 delta-like 1 (Drosophila) [ Homo sapiens ]
• Official Symbol: DLL1
• Synonyms: DLL1; delta-like 1 (Drosophila); delta (Drosophila) like 1; delta-like protein 1
• Gene ID: 28514
• mRNA Refseq: NM_005618
• Protein Refseq: NP_005609
• MIM: 606582
• Uniprot ID: O00548
• Chromosome Location: 6q13-q22.33
• Pathway: Delta-Notch Signaling Pathway, organism-specific biosystem; Notch receptor binds with a ligand, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Notch signaling pathway, conserved biosystem
• Function: Notch binding; calcium ion binding; protein binding