Recombinant human DEFB118, His-tagged

• Cat.No.: DEFB118-2453H
• Product Overview: Recombinant human DEFB118 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: DEFB118 is a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. Expression of this gene is regulated by androgen, and the encoded protein binds to sperm and exhibits antibacterial activity. This protein is found in a cluster with other beta-defensin genes on the long arm of chromosome 20.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT.
• Molecular Mass: 13.8kDa (126aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSYSGEKKC WNRSGHCRKQ CKDGEAVKDT CKNLRACCIP SNEDHRRVPA TSPTPLSDST PGIIDDILTVRFTTDYFEVS SKKDMVEESE AGRGTETSLP NVHHSS
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: DEFB118?defensin, beta 118 [?Homo sapiens?(human) ]
• Official Symbol: DEFB118
• Synonyms: DEFB118; ESC42; DEFB-18; ESP13.6; C20orf63; defensin, beta 118; beta-defensin 118; defensin, beta 18; epididymus specific clone 42; epididymal secretory protein 13.6
• Gene ID: 117285
• mRNA Refseq: NM_054112
• Protein Refseq: NP_473453
• MIM: 607650
• UniProt ID: Q96PH6
• Chromosome Location: 20q11.21
• Pathway: Beta defensins; Defensins; Immune System; Innate Immune System