Recombinant Human DEF6, GST-tagged

• Cat.No.: DEF6-11923H
• Product Overview: Recombinant Human DEF6 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 [PubMed 12923183]).
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: N-term-336a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: DEF6 differentially expressed in FDCP 6 homolog (mouse) [ Homo sapiens ]
• Official Symbol: DEF6
• Synonyms: DEF6; differentially expressed in FDCP 6 homolog (mouse); differentially expressed in FDCP (mouse homolog) 6; differentially expressed in FDCP 6 homolog; IBP; SLAT; SWAP 70 like adaptor protein of T cells; SWAP70L; DEF-6; IRF4-binding protein; SWAP-70-like adaptor protein of T cells
• Gene ID: 50619
• mRNA Refseq: NM_022047
• Protein Refseq: NP_071330
• MIM: 610094
• UniProt ID: Q9H4E7
• Chromosome Location: 6p21.33-p21.1
• Pathway: Regulation of RAC1 activity, organism-specific biosystem; Regulation of RhoA activity, organism-specific biosystem; T Cell Receptor Signaling Pathway, organism-specific biosystem