Recombinant Human DDX58 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: DDX58-2702H
• Product Overview: DDX58 MS Standard C13 and N15-labeled recombinant protein (NP_055129) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 106.4 kDa
• AA Sequence: MTTEQRRSLQAFQDYIRKTLDPTYI LSYMAPWFREEEVQYIQAEKNNKGP MEAATLFLKFLLELQEEGWFRGFLD ALDHAGYSGLYEAIESWDFKKIEKL EEYRLLLKRLQPEFKTRIIPTDIIS DLSECLINQECEEILQICSTKGMMA GAEKLVECLLRSDKENWPKTLKLAL EKERNKFSELWIVEKGIKDVETEDL EDKMETSDIQIFYQEDPECQNLSEN SCPPSEVSDTNLYSPFKPRNYQLEL ALPAMKGKNTIICAPTGCGKTFVSL LICEHHLKKFPQGQKGKVVFFANQI PVYEQQKSVFSKYFERHGYRVTGIS GATAENVPVEQIVENNDIIILTPQI LVNNLKKGTIPSLSIFTLMIFDECH NTSKQHPYNMIMFNYLDQKLGGSSG PLPQVIGLTASVGVGDAKNTDEALD YICKLCASLDASVIATVKHNLEELE QVVYKPQKFFRKVESRISDKFKYII AQLMRDTESLAKRICKDLENLSQIQ NREFGTQKYEQWIVTVQKACMVFQM PDKDEESRICKALFLYTSHLRKYND ALIISEHARMKDALDYLKDFFSNVR AAGFDEIEQDLTQRFEEKLQELESV SRDPSNENPKLEDLCFILQEEYHLN PETITILFVKTRALVDALKNWIEGN PKLSFLKPGILTGRGKTNQNTGMTL PAQKCILDAFKASGDHNILIATSVA DEGIDIAQCNLVILYEYVGNVIKMI QTRGRGRARGSKCFLLTSNAGVIEK EQINMYKEKMMNDSILRLQTWDEAV FREKILHIQTHEKFIRDSQEKPKPV PDKENKKLLCRKCKALACYTADVRV IEECHYTVLGDAFKECFVSRPHPKP KQFSSFEKRAKIFCARQNCSHDWGI HVKYKTFEIPVIKIESFVVEDIATG VQTLYSKWKDFHFEKIPFDPAEMSK TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: DDX58 DExD/H-box helicase 58 [ Homo sapiens (human) ]
• Official Symbol: DDX58
• Synonyms: DDX58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; probable ATP-dependent RNA helicase DDX58; DKFZp434J1111; FLJ13599; retinoic acid inducible gene I; RIG I; RNA helicase RIG I; RIG-1; RNA helicase RIG-I; DEAD box protein 58; retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; RIG-I; DKFZp686N19181
• Gene ID: 23586
• mRNA Refseq: NM_014314
• Protein Refseq: NP_055129
• MIM: 609631
• UniProt ID: O95786