Recombinant Human DDX20 Protein, MYC/DDK-tagged

• Cat.No.: DDX20-2472H
• Product Overview: Recombinant protein of human DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 (DDX20) with a C-terminal MYC/DDK tag was expressed in HEK293T cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs.
• Molecular Mass: 92.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: DDX20 DEAD-box helicase 20 [ Homo sapiens (human) ]
• Official Symbol: DDX20
• Synonyms: DDX20; DEAD-box helicase 20; DP103; GEMIN3; probable ATP-dependent RNA helicase DDX20; DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; DEAD box protein 20; DEAD box protein DP 103; DEAD-box protein DP103; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20, 103kD; SMN-interacting protein; component of gems 3; gemin-3; EC 3.6.4.13
• Gene ID: 11218
• mRNA Refseq: NM_007204
• Protein Refseq: NP_009135
• MIM: 606168
• UniProt ID: Q9UHI6