Recombinant Human DDR2, GST-tagged, Active

• Cat.No.: DDR2-294H
• Product Overview: Recombinant human DDR2 (467-end) was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW=70 kDa.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Protein Length: 467-end a.a.
• Description: DDR2 is a member of a novel subclass of RTKs containing a distinct extracellular region encompassing a factor VIII-like domain and is thought to be involved in the regulation of cell growth, differentiation, and metabolism. DDR2 plays a role in the regulation of collagen turnover mediated by smooth muscle cells in obstructive diseases of blood vessels and the lung.
• Sequence: 467-end.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: DDR2 discoidin domain receptor tyrosine kinase 2 [ Homo sapiens ]
• Synonyms: DDR2; discoidin domain receptor tyrosine kinase 2; TKT; MIG20a; NTRKR3; TYRO10; DDR2; discoidin domain receptor family, member 2; tyrosylprotein kinase; hydroxyaryl-protein kinase; cell migration-inducing protein 20; migration-inducing gene 16 protein; neurotrophic tyrosine kinase receptor related 3; EC 2.7.10.1; OTTHUMP00000032332; OTTHUMP00000038368; CD167 antigen-like family member B; CD167b antigen; Discoidin domain receptor 2; Neurotrophic tyrosine kinase, receptor-related 3; Receptor protein-tyrosine kinase TKT; Tyrosine-protein kinase TYRO10
• Gene ID: 4921
• mRNA Refseq: NM_001014796
• Protein Refseq: NP_001014796
• MIM: 191311
• UniProt ID: Q16832
• Chromosome Location: 1q23.3
• Function: transmembrane receptor protein tyrosine kinase activity; ATP binding; nucleotide binding; protein binding; receptor activity; transferase activity