Active Recombinant Human DDR2, GST-tagged

• Cat.No.: DDR2-820H
• Product Overview: Recombinant human DDR2 (467-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: DDR2 is a member of a novel subclass of RTKs containing a distinct extracellular region encompassing a factor VIII-like domain and is thought to be involved in the regulation of cell growth, differentiation, and metabolism. DDR2 plays a role in the regulation of collagen turnover mediated by smooth muscle cells in obstructive diseases of blood vessels and the lung.
• Source: Sf9 insect cells using baculovirus
• Species: Human
• Tag: GST
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Bio-activity: 5 nmol/min/mg
• Molecular Mass: ~70 kDa
• Protein length: 467-end
• Purity: >95%
• Applications: Kinase Assay, Western Blot
• Stability: 1yr at –70°C from date of shipment
• Storage: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1ug/ul

Gene Information

• Gene Name: DDR2 discoidin domain receptor tyrosine kinase 2 [ Homo sapiens ]
• Official Symbol: DDR2
• Synonyms: DDR2; discoidin domain receptor tyrosine kinase 2; discoidin domain receptor family, member 2 , NTRKR3, TYRO10; discoidin domain-containing receptor 2; TKT; tyrosylprotein kinase; hydroxyaryl-protein kinase; discoidin domain receptor 2; tyrosine-protein kinase TYRO10; CD167 antigen-like family member B; cell migration-inducing protein 20; migration-inducing gene 16 protein; receptor protein-tyrosine kinase TKT; discoidin domain receptor family, member 2; neurotrophic tyrosine kinase receptor related 3; neurotrophic tyrosine kinase, receptor-related 3; discoidin domain-containing receptor tyrosine kinase 2; MIG20a; NTRKR3; TYRO10
• Gene ID: 4921
• mRNA Refseq: NM_001014796
• Protein Refseq: NP_001014796
• MIM: 191311
• UniProt ID: Q16832
• Chromosome Location: 1q12-q23
• Pathway: Endochondral Ossification, organism-specific biosystem
• Function: ATP binding; collagen binding; kinase activity; nucleotide binding; protein tyrosine kinase collagen receptor activity; receptor activity; transmembrane receptor protein tyrosine kinase activity