Recombinant Human DDAH1, His-tagged

• Cat.No.: DDAH1-26449TH
• Product Overview: Recombinant full length Human DDAH1 with an N terminal His tag; 308 amino acids with a predicted MWt 33.5kDa including tag,.

Specification

• Description: This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity.
• Protein length: 285 amino acids
• Conjugation: HIS
• Molecular Weight: 33.500kDa inclusive of tags
• Source: E. coli
• Tissue specificity: Detected in brain, liver, kidney and pancreas, and at low levels in skeletal muscle.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 50mM Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMGSMAGLGHPAAFGRATHAVVRALPESLGQHALRSAKGEEVDVARAERQHQLYVGVLGSKLGLQVVELPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEVDMMKEALEKLQLNIVEMKDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPEEYPESAKVYEKLKDHMLIPVSMSELEKVDGLLTCCSVLINKKVDS
• Sequence Similarities: Belongs to the DDAH family.

Gene Information

• Gene Name: DDAH1 dimethylarginine dimethylaminohydrolase 1 [ Homo sapiens ]
• Official Symbol: DDAH1
• Synonyms: DDAH1; dimethylarginine dimethylaminohydrolase 1; N(G),N(G)-dimethylarginine dimethylaminohydrolase 1; DDAH
• Gene ID: 23576
• mRNA Refseq: NM_001134445
• Protein Refseq: NP_001127917
• MIM: 604743
• Uniprot ID: O94760
• Chromosome Location: 1p22
• Function: amino acid binding; catalytic activity; dimethylargininase activity; dimethylargininase activity; hydrolase activity