Recombinant Human DCPS protein

• Cat.No.: DCPS-1571H
• Product Overview: Recombinant full-length human DCPS was expressed in and purified from E. coli.

Specification

• Description: This gene encodes a member of the histidine triad family of pyrophosphatases that removes short mRNA fragments containing the 5′ mRNA cap structure, which appear in the 3′ → 5′ mRNA decay pathway, following deadenylation and exosome-mediated turnover. This enzyme hydrolyzes the triphosphate linkage of the cap structure (7-methylguanosine nucleoside triphosphate) to yield 7-methylguanosine monophosphate and nucleoside diphosphate. It protects the cell from the potentially toxic accumulation of these short, capped mRNA fragments, and regulates the activity of other cap-binding proteins, which are inhibited by their accumulation. It also acts as a transcript-specific modulator of pre-mRNA splicing and microRNA turnover.
• Source: E. coli
• Species: Human
• Form: 50 mM Tris-HCl (pH 8.0), 500 mM NaCl and 10% glycerol.
• Molecular Mass: 39 kDa
• Storage: Stable for 12 months at -80 centigrade from date of shipment. Please aliquot to avoid repeated freezing and thawing.
• Concentration: 0.3-0.8 mg/ml
• Tag: Non

Gene Information

• Gene Name: DCPS decapping enzyme, scavenger [ Homo sapiens ]
• Official Symbol: DCPS
• Synonyms: DCPS; decapping enzyme, scavenger; scavenger mRNA-decapping enzyme DcpS; HINT 5; HSL1; HSPC015; DCS-1; mRNA decapping enzyme; heat shock-like protein 1; histidine triad protein member 5; hint-related 7meGMP-directed hydrolase; homolog of C. elegans 7meGMP-directed hydrolase dcs-1; HINT-5
• Gene ID: 28960
• mRNA Refseq: NM_014026
• Protein Refseq: NP_054745
• MIM: 610534
• UniProt ID: Q96C86