Recombinant Human DAOA Protein, His-tagged

• Cat.No.: DAOA-367H
• Product Overview: Recombinant Human DAOA, transcript variant 11, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: This gene encodes a protein that may function as an activator of D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Studies also suggest that one encoded isoform may play a role in mitochondrial function and dendritic arborization. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Form: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 17.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: DAOA?D-amino acid oxidase activator [?Homo sapiens?(human) ]
• Official Symbol: DAOA
• Synonyms: DAOA; D-amino acid oxidase activator; LG72; SG72; D-amino acid oxidase activator; G72 transcript; schizophrenia- and bipolar disorder-associated protein G72
• Gene ID: 267012
• mRNA Refseq: NM_172370
• Protein Refseq: NP_758958
• MIM: 607408
• UniProt ID: P59103