Recombinant Human CSK, His-tagged

• Cat.No.: CSK-26133TH
• Product Overview: Recombinant full length human CSK with an N-terminal 6X-His tag; amino acids 1-450 , 50kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 450 amino acids
• Description: C-src tyrosine kinase, also known as CSK, is a human protein and gene. It includes an SH2 domain, an SH3 domain, and a tyrosine kinase domain.
• Conjugation: HIS
• Molecular Weight: 50.000kDa
• Tissue specificity: Expressed in lung and macrophages.
• Form: Liquid
• Purity: Immunogen affinity purified
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.Contains 1 protein kinase domain.Contains 1 SH2 domain.Contains 1 SH3 domain.

Gene Information

• Gene Name: CSK c-src tyrosine kinase [ Homo sapiens ]
• Official Symbol: CSK
• Synonyms: CSK; c-src tyrosine kinase; tyrosine-protein kinase CSK
• Gene ID: 1445
• mRNA Refseq: NM_001127190
• Protein Refseq: NP_001120662
• MIM: 124095
• Uniprot ID: P41240
• Chromosome Location: 15q24.1
• Pathway: Adaptive Immune System, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; BCR signaling pathway, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem; Costimulation by the CD28 family, organism-specific biosystem
• Function: ATP binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; proline-rich region binding; protein C-terminus binding