Recombinant Human CRLF3 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : CRLF3-458H
Product Overview : CRLF3 MS Standard C13 and N15-labeled recombinant protein (NP_057070) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Description : This gene encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase. Studies of the related rat protein suggest that it may regulate neuronal morphology and synaptic vesicle biogenesis. This gene is one of several genes located in the neurofibromatosis type I tumor suppressor region on the q arm of chromosome 17, a region that is subject to microdeletions, duplications, chromosomal breaks and rearrangements. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2 and 5.
Source : HEK293
Species : Human
Tag : Myc&DDK
Molecular Mass : 49.8 kDa
AA Sequence : MRGAMELEPELLLQEARENVEAAQSYRRELGHRLEGLREARRQIKESASQTRDVLKQHFNDLKGTLGKLLDERLVTLLQEVDTIEQETIKPLDDCQKLIEHGVNTAEDLVREGEIAMLGGVGEENEKLWSFTKKASHIQLDSLPEVPLLVDVPCLSAQLDDSILNIVKDHIFKHGTVASRPPVQIEELIEKPGGIIVRWCKVDDDFTAQDYRLQFRKCTSNHFEDVYVGSETEFIVLHIDPNVDYQFRVCARGDGRQEWSPWSVPQIGHSTLVPHEWTAGFEGYSLSSRRNIALRNDSESSGVLYSRAPTYFCGQTLTFRVETVGQPDRRDSIGVCAEKQDGYDSLQRDQAVCISTNGAVFVNGKEMTNQLPAVTSGSTVTFDIEAVTLGTTSNNEGGHFKLRVTISSNNREVVFDWLLDQSCGSLYFGCSFFYPGWKVLVFTRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name CRLF3 cytokine receptor-like factor 3 [ Homo sapiens (human) ]
Official Symbol CRLF3
Synonyms CRLF3; cytokine receptor-like factor 3; CREME9; CYTOR4; cytokine receptor-like molecule 9; cytokine receptor related protein 4; cytokine receptor-related protein 4; type I cytokine receptor like factor; type I cytokine receptor-like factor p48; FRWS; p48.2; CREME-9; MGC20661;
Gene ID 51379
mRNA Refseq NM_015986
Protein Refseq NP_057070
MIM 614853
UniProt ID Q8IUI8

Not For Human Consumption!

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