Recombinant Human CRLF3, GST-tagged

• Cat.No.: CRLF3-11584H
• Product Overview: Recombinant Human CRLF3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase. Studies of the related rat protein suggest that it may regulate neuronal morphology and synaptic vesicle biogenesis. This gene is one of several genes located in the neurofibromatosis type I tumor suppressor region on the q arm of chromosome 17, a region that is subject to microdeletions, duplications, chromosomal breaks and rearrangements. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2 and 5.
• Protein length: C-term-303a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CRLF3 cytokine receptor-like factor 3 [ Homo sapiens ]
• Official Symbol: CRLF3
• Synonyms: CRLF3; cytokine receptor-like factor 3; CREME9; CYTOR4; cytokine receptor-like molecule 9; cytokine receptor related protein 4; cytokine receptor-related protein 4; type I cytokine receptor like factor; type I cytokine receptor-like factor p48; FRWS; p48.2; CREME-9; MGC20661
• Gene ID: 51379
• mRNA Refseq: NM_015986
• Protein Refseq: NP_057070
• UniProt ID: Q8IUI8
• Chromosome Location: 17q11.2