Recombinant Full Length Human CRLF3 Protein, GST-tagged

• Cat.No.: CRLF3-2070HF
• Product Overview: Human CRLF3 full-length ORF ( AAH23567.2, 1 a.a. - 442 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase. Studies of the related rat protein suggest that it may regulate neuronal morphology and synaptic vesicle biogenesis. This gene is one of several genes located in the neurofibromatosis type I tumor suppressor region on the q arm of chromosome 17, a region that is subject to microdeletions, duplications, chromosomal breaks and rearrangements. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2 and 5. [provided by RefSeq, Aug 2012]
• Molecular Mass: 76.2 kDa
• Protein length: 442 amino acids
• AA Sequence: MRGAMELEPELLLQEARENVEAAQSYRRELGHRLEGLREARRQIKESASQTRDVLKQHFNDLKGTLGKLLDERLVTLLQEVDTIEQETIKPLDDCQKLIEHGVNTAEDLVREGEIAMLGGVGEENEKLWSFTKKASHIQLDSLPEVPLLVDVPCLSAQLDDSILNIVKDHIFKHGTVASRPPVQIEELIEKPGGIIVRWCKVDDDFTAQDYRLQFRKCTSNHFEDVYVGSETEFIVLHIDPNVDYQFRVCARGDGRQEWSPWSVPQIGHSTLVPHEWTAGFEGYSLSSRRNIALRNDSESSGVLYSRAPTYFCGQTLTFRVETVGQPDRRDSIGVCAEKQDGYDSLQRDQAVCISTNGAVFVNGKEMTNQLPAVTSGSTVTFDIEAVTLGTTSNNEGGHFKLRVTISSNNREVVFDWLLDQSCGSLYFGCSFFYPGWKVLVF
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CRLF3 cytokine receptor-like factor 3 [ Homo sapiens ]
• Official Symbol: CRLF3
• Synonyms: CRLF3; cytokine receptor-like factor 3; CREME9; CYTOR4; cytokine receptor-like molecule 9; cytokine receptor related protein 4; cytokine receptor-related protein 4; type I cytokine receptor like factor; type I cytokine receptor-like factor p48; FRWS; p48.2; CREME-9; MGC20661
• Gene ID: 51379
• mRNA Refseq: NM_015986
• Protein Refseq: NP_057070
• MIM: 614853
• UniProt ID: Q8IUI8