Recombinant Human CRLF1 protein, His & GST-tagged

• Cat.No.: CRLF1-1428H
• Product Overview: Recombinant Human CRLF1 aa. (Pro138~Arg422 (Accession # O75462) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Protein Length: Pro138~Arg422
• Description: This gene encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 62.2kDa.
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 9.2.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: CRLF1 cytokine receptor like factor 1 [ Homo sapiens (human) ]
• Official Symbol: CRLF1
• Synonyms: CRLF1; cytokine receptor like factor 1; CLF; NR6; CISS; CISS1; CLF-1; zcytor5; cytokine receptor-like factor 1; class I cytokine receptor; cytokine type 1 receptor CRLP-1; cytokine-like factor 1
• Gene ID: 9244
• mRNA Refseq: NM_004750.4
• Protein Refseq: NP_004741.1
• UniProt ID: O75462