Recombinant Human CRLF1, Fc-tagged

• Cat.No.: CRLF1-2145H
• Product Overview: A DNA sequence encoding the human CLCF1 (NP_037378.1)(Leu28-Phe225) was expressed with the fused Fc region of human IgG1 at the N-terminus.

Specification

• Species: Human
• Source: Human Cells
• Tag: Fc
• Description: Cytokine receptor-like factor 1 is a protein that in humans is encoded by the CRLF1 gene. CRLF1 is a novel soluble protein and shares homology with members of the cytokine type I receptor family.
• Predicted N Terminal: Glu
• Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization.
• Molecular Mass: The recombinant human CLCF1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 458 amino acids and has a predicted molecular mass of 50.7 kDa. The apparent molecular mass of the protein is approximately 54 kDa in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: > 85 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70℃.
• Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Gene Information

• Gene Name: CRLF1 cytokine receptor-like factor 1 [ Homo sapiens ]
• Official Symbol: CRLF1
• Synonyms: CRLF1; cytokine receptor-like factor 1; CISS; CISS1; CLF; CLF 1; cold induced sweating syndrome; cytokine-like factor 1; class I cytokine receptor; cytokine type 1 receptor CRLP-1; NR6; CLF-1; zcytor5
• Gene ID: 9244
• mRNA Refseq: NM_004750
• Protein Refseq: NP_004741
• MIM: 604237
• UniProt ID: O75462
• Chromosome Location: 19p12
• Function: contributes_to ciliary neurotrophic factor receptor binding; contributes_to cytokine activity; cytokine binding; protein binding; protein heterodimerization activity; receptor activity