Recombinant Human CRKL Protein, MYC/DDK-tagged

• Cat.No.: CRKL-3324H
• Product Overview: Recombinant Human CRKL protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 33.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like [ Homo sapiens ]
• Official Symbol: CRKL
• Synonyms: v-crk avian sarcoma virus CT10 oncogene homolog-like; v-crk sarcoma virus CT10 oncogene homolog (avian)-like
• Gene ID: 1399
• mRNA Refseq: NM_005207
• Protein Refseq: NP_005198
• MIM: 602007
• UniProt ID: P46109