Recombinant Human CRISP1 Protein, GST-tagged

• Cat.No.: CRISP1-1881H
• Product Overview: Human CRISP1 full-length ORF ( NP_001122.2, 1 a.a. - 249 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: GST
• Description: Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. The protein encoded by this gene is a member of the cysteine-rich secretory protein (CRISP) family. It is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head, where it plays a role in sperm-egg fusion. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
• Molecular Mass: 54.9 kDa
• AA Sequence: MEIKHLLFLVAAACLLPMLSMKKKSARDQFNKLVTDLPNVQEEIVNIHNALRRRVVPPASNMLKMSWSEEAAQNARIFSKYCDMTESNPLERRLPNTFCGENMHMTSYPVSWSSVIGVWYSESTSFKHGEWTTTDDDITTDHYTQIVWATSYLIGCAIASCRQQGSPRYLYVCHYCHEGNDPETKNEPYKTGVPCEACPSNCEDKLCTNPCIYYDEYFDCDIQVHYLGCNHSTTILFCKATCLCDTEIK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CRISP1 cysteine-rich secretory protein 1 [ Homo sapiens ]
• Official Symbol: CRISP1
• Synonyms: CRISP1; cysteine-rich secretory protein 1; acidic epididymal glycoprotein like 1 , AEGL1; ARP; CRISP 1; HSCRISP1D; HSCRISP1G; HUMARP; AEG-like protein; AEG-related protein; acidic epididymal glycoprotein-like 1; acidic epididymal glycoprotein homolog; cysteine-rich secretory protein-1 delta; AEGL1; CRISP-1
• Gene ID: 167
• mRNA Refseq: NM_001131
• Protein Refseq: NP_001122
• MIM: 601193
• UniProt ID: P54107