Recombinant Human CR2 protein, His & GST-tagged

• Cat.No.: CR2-836H
• Product Overview: Recombinant Human CR2 aa. (Lys729~Ser957 (Accession # P20023)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Description: This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 57.5kDa
• Protein length: Lys729~Ser957
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 6.5.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: CR2 complement C3d receptor 2 [ Homo sapiens (human) ]
• Official Symbol: CR2
• Synonyms: CR; C3DR; CD21; CVID7; SLEB9; EBV receptor; complement component (3d/Epstein Barr virus) receptor 2; complement component 3d receptor 2; complement receptor type 2
• Gene ID: 1380
• mRNA Refseq: NM_001006658.2
• Protein Refseq: NP_001006659.1
• UniProt ID: P20023