Recombinant Human CPEB1, GST-tagged

• Cat.No.: CPEB1-11516H
• Product Overview: Recombinant Human CPEB1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a member of the cytoplasmic polyadenylation element (CPE) binding protein family. This highly conserved protein binds to a specific RNA sequence called the CPE found in the 3 UTR of some mRNAs. Similar proteins in Xenopus and mouse function to induce cytoplasmic polyadenylation of dormant mRNAs with short polyA tails, resulting in their translation. Members of this protein family regulate translation of cyclin B1 during embryonic cell divisions. Multiple transcript variants encoding different isoforms have been found for this gene.
• Protein length: C-term-300a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CPEB1 cytoplasmic polyadenylation element binding protein 1 [ Homo sapiens ]
• Official Symbol: CPEB1
• Synonyms: CPEB1; cytoplasmic polyadenylation element binding protein 1; cytoplasmic polyadenylation element-binding protein 1; CPEB; FLJ13203; h-CEBP; hCPEB-1; CPE-binding protein 1; CEBP; CPE-BP1; MGC34136; MGC60106
• Gene ID: 64506
• mRNA Refseq: NM_001079533
• Protein Refseq: NP_001073001
• MIM: 607342
• UniProt ID: Q9BZB8
• Chromosome Location: 15q25.1
• Pathway: Aurora A signaling, organism-specific biosystem; Dorso-ventral axis formation, organism-specific biosystem; Dorso-ventral axis formation, conserved biosystem; Oocyte meiosis, organism-specific biosystem; Oocyte meiosis, conserved biosystem; Progesterone-mediated oocyte maturation, organism-specific biosystem; Progesterone-mediated oocyte maturation, conserved biosystem
• Function: RNA binding; nucleotide binding