Recombinant Human COX5A, His-tagged

• Cat.No.: COX5A-7085H
• Product Overview: Recombinant human COX5A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: COX5A, also known as COX, COX-VA and VA, belongs to the cytochrome c oxidase subunit 5A family. Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. COX5A is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl,10% glycerol, 2mM DTT
• Molecular Mass: 4.9kDa (132aa)
• Protein length: 42-150aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSSHGSQET DEEFDARWVT YFNKPDIDAW ELRKGINTLV TYDMVPEPKI IDAALRACRR LNDFASTVRI LEVVKDKAGP HKEIYPYVIQ ELRPTLNELG ISTPEELGLD KV
• Purity: >95% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml

Gene Information

• Gene Name: COX5A cytochrome c oxidase subunit Va [ Homo sapiens ]
• Official Symbol: COX5A
• Synonyms: COX5A; cytochrome c oxidase subunit Va; cytochrome c oxidase subunit 5A, mitochondrial; cytochrome c oxidase polypeptide Va; mitochondrial cytochrome c oxidase subunit Va; cytochrome c oxidase polypeptide, mitochondrial; VA; COX; COX-VA
• Gene ID: 9377
• mRNA Refseq: NM_004255
• Protein Refseq: NP_004246
• MIM: 603773
• UniProt ID: P20674
• Chromosome Location: 15q25
• Pathway: Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Arachidonate Epoxygenase / Epoxide Hydrolase, organism-specific biosystem; Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Cytochrome c oxidase, organism-specific biosystem; Cytochrome c oxidase, conserved biosystem
• Function: cytochrome-c oxidase activity; electron carrier activity; metal ion binding