Recombinant Human COL6A1, His-tagged
Cat.No. : | COL6A1-11438H |
Product Overview : | Recombinant Human COL6A1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
Availability | March 14, 2025 |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Protein Length : | 770-1028a.a. |
Description : | The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name | COL6A1 collagen, type VI, alpha 1 [ Homo sapiens ] |
Official Symbol | COL6A1 |
Synonyms | COL6A1; collagen, type VI, alpha 1; collagen alpha-1(VI) chain; alpha 1 (VI) chain (61 AA); collagen VI, alpha-1 polypeptide; OPLL; |
Gene ID | 1291 |
mRNA Refseq | NM_001848 |
Protein Refseq | NP_001839 |
MIM | 120220 |
UniProt ID | P12109 |
Chromosome Location | 21q22.3 |
Pathway | Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; NCAM signaling for neurite out-growth, organism-specific biosystem; |
Function | platelet-derived growth factor binding; |
◆ Recombinant Proteins | ||
COL6A1-1659H | Recombinant Human COL6A1 Protein, GST-tagged | +Inquiry |
COL6A1-11438H | Recombinant Human COL6A1, His-tagged | +Inquiry |
COL6A1-9677HFL | Recombinant Full Length Human COL6A1, Flag-tagged | +Inquiry |
COL6A1-1767H | Recombinant Human COL6A1 Protein (Asn770-Gly1028), N-His tagged | +Inquiry |
COL6A1-1870H | Recombinant Human Collagen, Type VI, Alpha 1 | +Inquiry |
◆ Native Proteins | ||
COL6-116H | Native Human Collagen type VI | +Inquiry |
COL6A1-001B | Native Bovine COL6A1 Protein | +Inquiry |
Not For Human Consumption!
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