Recombinant Human CLUL1, His-tagged

• Cat.No.: CLUL1-70H
• Product Overview: Recombinant Human Clusterin-Like Protein 1/CLUL1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala21-Ala442) of Human CLUL1 fused with a polyhistidine tag at the C-terminus.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• ProteinLength: 21-442 a.a.
• Description: Clusterin-Like Protein 1 (CLUL1) is a secreted protein that belongs to the clusterin family. CLUL1 is synthesized as a 466 amino acid precursor that contains a 20 amino acid signal sequence, and a 446 amino acid mature chain. CLUL1 is expressed predominantly by cone photoreceptors of the retina. It has been shown that CLUL1 expression is down-regulated in some forms of retinal disease.
• AA Sequence: APTWKDKTAISENLKSFSEVGEIDADEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQ EALKLLNEVQEHLEEEERLCRESLADSWGECRSCLENNCMRIYTTCQPSWSSVKNKIERFFRKIY QFLFPFHEDNEKDLPISEKLIEEDAQLTQMEDVFSQLTVDVNSLFNRSFNVFRQMQQEFDQTFQS HFISDTDLTEPYFFPAFSKEPMTKADLEQCWDIPNFFQLFCNFSVSIYESVSETITKMLKAIEDL PKQDKAPDHGGLISKMLPGQDRGLCGELDQNLSRCFKFHEKCQKCQAHLSEDCPDVPALHTELDE AIRLVNVSNQQYGQILQMTRKHLEDTAYLVEKMRGQFGWVSELANQAPETEIIFNSIQVVPRIHE GNISKQDETMMTDLSILPSSNFTLKIPLEESAVDHHHHHH
• Endotoxin: Less than 0.1 ng/μg (1 IEU/μg).
• Purity: Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.

Gene Information

• Gene Name: CLUL1 clusterin-like 1 (retinal) [ Homo sapiens ]
• Official Symbol: CLUL1
• Synonyms: CLUL1; clusterin-like 1 (retinal); clusterin-like protein 1; retinal-specific clusterin-like protein; RA337M
• Gene ID: 27098
• mRNA Refseq: NM_014410
• Protein Refseq: NP_055225
• UniProt ID: Q15846
• Chromosome Location: 18p11.32