Recombinant Human CLNK Protein, MYC/DDK-tagged

• Cat.No.: CLNK-3251H
• Product Overview: Recombinant Human CLNK protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603; BLNK, MIM 604515). MIST plays a role in the regulation of immunoreceptor signaling, including PLC-gamma (PLCG1; MIM 172420)-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999 [PubMed 10562326]; Goitsuka et al., 2000, 2001 [PubMed 10744659] [PubMed 11463797]).
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 49.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CLNK cytokine-dependent hematopoietic cell linker [ Homo sapiens ]
• Official Symbol: CLNK
• Synonyms: MIST
• Gene ID: 116449
• mRNA Refseq: NM_052964
• Protein Refseq: NP_443196
• MIM: 611434
• UniProt ID: Q7Z7G1