CLNK
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Official Full Name
cytokine-dependent hematopoietic cell linker -
Overview
MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603; BLNK, MIM 604515). MIST plays a role in the;regulation of immunoreceptor signaling, including PLC-gamma (PLCG1; MIM 172420)-mediated B cell antigen receptor (BCR);signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999 (PubMed;10562326); Goitsuka et al., 2000, 2001 (PubMed 10744659) (PubMed 11463797)). -
Synonyms
CLNK;cytokine-dependent hematopoietic cell linker;mast cell immunoreceptor signal transducer;MIST;MGC35197
Recombinant Proteins
- Human
- Mouse
- Wheat Germ
- Mammalian Cells
- HEK293
- In Vitro Cell Free System
- GST
- His
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CLNK-1508H | Recombinant Human CLNK Protein, GST-tagged | Wheat Germ | Human | GST |
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| CLNK-3594M | Recombinant Mouse CLNK Protein | Mammalian Cells | Mouse | His |
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| CLNK-1764M | Recombinant Mouse CLNK Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CLNK-1764M-B | Recombinant Mouse CLNK Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| CLNK-1884HF | Recombinant Full Length Human CLNK Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 428 amino acids |
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| Clnk-2195M | Recombinant Mouse Clnk Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| CLNK-3251H | Recombinant Human CLNK Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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Involved Pathway
CLNK involved in several pathways and played different roles in them. We selected most pathways CLNK participated on our site, such as XPodNet - protein-protein interactions in the podocyte expanded by STRING, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLNK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| XPodNet - protein-protein interactions in the podocyte expanded by STRING | OASL2,CHD1L,TENC1,CMIP,GMCL1,CDC42EP5,ZFP423,FRAS1,O3far1,SNTB1 |
Protein Function
CLNK has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CLNK itself. We selected most functions CLNK had, and list some proteins which have the same functions with CLNK. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | EPS15L1,Clec4n,CXCL10,SETBP1,CCDC135,TEKT4,NPM3,MAP2,CD46,IL4R |
Interacting Protein
CLNK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLNK here. Most of them are supplied by our site. Hope this information will be useful for your research of CLNK.
Fyb;Fgr;Lyn;Fyn;Skap2;Skap1
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