Recombinant Human CLN5 Protein, GST-tagged

• Cat.No.: CLN5-1506H
• Product Overview: Human CLN5 full-length ORF (BAG52069.1, 1 a.a. - 358 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: GST
• Description: This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.[provided by RefSeq, Oct 2008]
• Molecular Mass: 67.8 kDa
• AA Sequence: MAQEVDTAQGAEMRRGAGAARGRASWCWALALLWLAVVPGWSRVSGIPSRRHWPVPCKRFDFRPKPDPYCQAKYTFCPTGSPIPVMEGDDDTEVFRLQAPVWEFKYGDLLGHLKIMHDAIGFRSTLTGKNYTMEWYELFQLGNCTFPHLRPEMDAPFWCNQGAACFFEGIDDVHWKENGTLVQVATISGNMFNQMAKWVKQDNETGIYYETWNVKASPEKGAETWFDSYDCSKFVLRTFNKLAEFGAEFKNIETNYTRIFLYSGEPTYLGNETSVFGPTGNKTLGLAIKRFYYPFKPHLPTKEFLLSLLQIFDAVIVHKQFYLFYNFEYWFLPMKFPFIKITYEEIPLPIRNKTLSGL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CLN5 CLN5, intracellular trafficking protein [ Homo sapiens (human) ]
• Official Symbol: CLN5
• Synonyms: CLN5; CLN5, intracellular trafficking protein; Ceroid-Lipofuscinosis, Neuronal 5; Ceroid-Lipofuscinosis Neuronal Protein 5; Protein CLN5; NCL; ceroid-lipofuscinosis neuronal protein 5; ceroid-lipofuscinosis, neuronal 5
• Gene ID: 1203
• mRNA Refseq: NM_006493
• Protein Refseq: NP_006484
• MIM: 608102
• UniProt ID: O75503