Recombinant Human Ciliary Neurotrophic Factor (rDNA derived) Reference standard

Cat.No. : CNTF-139H
Product Overview : The CNTF used in this preparation is the human form of the molecule with an N-terminal methionine residue, synthesized in E. coli by recombinant DNA technology.
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Species : Human
Source : E.coli
Tag : Non
Enzyme Unit : The assigned potency of CNTF is 8000 units per ampoule.
Usage : No attempt should be made to weigh out any portion of the freeze-dried material prior to reconstitution. For all practical purposes, each ampoule contains the same quantity of CNTF. The entire contents of each ampoule should be completely dissolved in a known volume of suitable solvent. It is recommended that, when possible, buffer containing carrier protein should be used to minimize loss by surface adsorption.
Notes : This preparation is not for administration to humans. The preparation contains material of human origin, and either the final product or the source materials, from which it is derived, have been tested and found negative for HBsAg, anti-HIV and HCV RNA. As with all materials of biological origin, this preparation should be regarded as potentially hazardous to health. It should be used and discarded according to your own laboratorys safety procedures. Such safety procedures should include the wearing of protective gloves and avoiding the generation of aerosols. Care should be exercised in opening ampoules or vials, to avoid cuts.
Stability : Reference materials are held at Creative Biomart within assured, temperature- controlled storage facilities and they should be stored on receipt as indicated on the label. Accelerated degradation studies have indicated that this material is suitably stable, when stored at -20°C or below, for the assigned values to remain valid until the material is withdrawn or replaced. These studies have also shown that the material is suitably stable for shipment at ambient temperature without any effect on the assigned values. Users who have data supporting any deterioration in the characteristics of any reference preparation are encouraged to contact Creative Biomart.
Storage : The ampoules are shipped at ambient temperature. Unopened ampoules should be stored at -20 °C in the dark. Ampoule contents should be used freshly reconstituted. Some loss of biological activity was observed on freezing and thawing reconstituted solution. The ampoules do not contain bacteriostat and solutions of the ampouled material should not be assumed to be sterile. Please note: because of the inherent stability of lyophilized material, Creative Biomart may ship these materials at ambient temperature.
Gene Name CNTF ciliary neurotrophic factor [ Homo sapiens ];
Official Symbol CNTF
Synonyms CNTF; ciliary neurotrophic factor; HCNTF;
Gene ID 1270
mRNA Refseq NM_000614
Protein Refseq NP_000605
MIM 118945
UniProt ID P26441
Chromosome Location 11q12
Pathway Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem;
Function ciliary neurotrophic factor receptor binding; cytokine activity; growth factor activity; interleukin-6 receptor binding;

Not For Human Consumption!

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