Species : |
Human |
Source : |
HEK293 |
Tag : |
Non |
Protein Length : |
1-200aa |
Description : |
The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. |
Tag : |
Non |
Molecular Mass : |
23.3 kDa |
Endotoxin : |
Less than 1.0 EU/μg by the LAL method. |
Purity : |
>95% as determined by SDS-PAGE. |
Storage : |
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Storage Buffer : |
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol. |
Reconstitution : |
Reconstitute at 250 μg/mL in sterile water. |