Recombinant Human CHST3, GST-tagged

• Cat.No.: CHST3-11229H
• Product Overview: Recombinant Human CHST3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes an enzyme which catalyzes the sulfation of chondroitin, a proteoglycan found in the extracellular matrix and most cells which is involved in cell migration and differentiation. Mutations in this gene are associated with spondylepiphyseal dysplasia and humerospinal dysostosis.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 46-479a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 [ Homo sapiens ]
• Official Symbol: CHST3
• Synonyms: CHST3; carbohydrate (chondroitin 6) sulfotransferase 3; carbohydrate sulfotransferase 3; C6ST; C6ST1; GST-0; C6ST-1; chondroitin 6-O-sulfotransferase 1; galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0; HSD
• Gene ID: 9469
• mRNA Refseq: NM_004273
• Protein Refseq: NP_004264
• MIM: 603799
• UniProt ID: Q7LGC8
• Chromosome Location: 10q22.1
• Pathway: Glycosaminoglycan biosynthesis - chondroitin sulfate, organism-specific biosystem; Glycosaminoglycan biosynthesis - chondroitin sulfate, conserved biosystem; chondroitin sulfate biosynthesis, organism-specific biosystem; chondroitin sulfate biosynthesis, conserved biosystem; chondroitin sulfate biosynthesis (late stages), organism-specific biosystem; chondroitin sulfate biosynthesis (late stages), conserved biosystem
• Function: chondroitin 6-sulfotransferase activity; proteoglycan sulfotransferase activity; sulfotransferase activity; transferase activity