Recombinant Human CHST15, GST-tagged

• Cat.No.: CHST15-11228H
• Product Overview: Recombinant Human CHST15 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: Chondroitin sulfate (CS) is a glycosaminoglycan which is an important structural component of the extracellular matrix and which links to proteins to form proteoglycans. Chondroitin sulfate E (CS-E) is an isomer of chondroitin sulfate in which the C-4 and C-6 hydroxyl groups are sulfated. This gene encodes a type II transmembrane glycoprotein that acts as a sulfotransferase to transfer sulfate to the C-6 hydroxal group of chondroitin sulfate. This gene has also been identified as being co-expressed with RAG1 in B-cells and as potentially acting as a B-cell surface signaling receptor. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 103-451a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 [ Homo sapiens ]
• Official Symbol: CHST15
• Synonyms: CHST15; carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15; carbohydrate sulfotransferase 15; B cell RAG associated protein; BRAG; GALNAC4S 6ST; KIAA0598; N acetylgalactosamine 4 sulfate 6 O sulfotransferase; hBRAG; B-cell RAG-associated gene protein; B cell RAG associated protein (GALNAC4S-6ST); N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase; GALNAC4S-6ST; RP11-47G11.1; MGC34346; DKFZp781H1369
• Gene ID: 51363
• mRNA Refseq: NM_014863
• Protein Refseq: NP_055678
• MIM: 608277
• UniProt ID: Q7LFX5
• Chromosome Location: 10q26
• Pathway: B Cell Receptor Signaling Pathway, organism-specific biosystem; Glycosaminoglycan biosynthesis - chondroitin sulfate, organism-specific biosystem; Glycosaminoglycan biosynthesis - chondroitin sulfate, conserved biosystem; chondroitin sulfate biosynthesis, organism-specific biosystem; chondroitin sulfate biosynthesis, conserved biosystem; chondroitin sulfate biosynthesis (late stages), organism-specific biosystem; chondroitin sulfate biosynthesis (late stages), conserved biosystem
• Function: 3-phosphoadenosine 5-phosphosulfate binding; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity; transferase activity