Recombinant Human Chromosome 20 0pen Reading Frame 20, His-tagged

• Cat.No.: C20orf20-1315H
• Product Overview: Recombinant human C20orf20 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: C20orf20 protein, also known as MRGBP, is a 204 amino acid protein which is a part of the NuA4 histone acetyltransferase (HAT) complex that acts to acetylate histone H2A and H4. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. MRGBP has potential to interact with MORF4L1/MRG15 and MORF4L2/MRGX.
• Form: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 20% glycerol, 0.2 M NaCl.
• Molecular Weight: 24.5 kDa (224 aa) confirmed by MALDI-TOF
• Purity: > 85% by SDS-PAGE
• Concentration: 0.5 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGEAEVGGGG AAGDKGPGEA ATSPAEETVV WSPEVEVCLF HAMLGHKPVG VNRHFHMICI RDKFSQNIGR QVPSKVIWDH LSTMYDMQAL HESEILPFPN PERNFVLPEE IIQEVREGKV MIEEEMKEEM KEDVDPHNGA DDVFSSSGSL GKASEKSSKD KEKNSSDLGC KEGADKRKRS RVTDKVLTAN SNPSSPSAAK RRRT
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: C20orf20 chromosome 20 open reading frame 20 [ Homo sapiens ]
• Official Symbol: C20orf20
• Synonyms: C20orf20; chromosome 20 open reading frame 20; Eaf7; MRGBP; URCC4; MRG15BP; FLJ10914; MRG-binding protein; OTTHUMP00000031512; MRG (MORF4-related gene)-binding protein
• Gene ID: 55257
• mRNA Refseq: NM_018270
• Protein Refseq: NP_060740
• MIM: 611157
• UniProt ID: Q9NV56
• Chromosome Location: 20q13.33