C20orf20
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Official Full Name
chromosome 20 open reading frame 20 -
Overview
Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. -
Synonyms
C20ORF20;chromosome 20 open reading frame 20;MRG-binding protein;Eaf7;FLJ10914;MRG15BP;MRGBP;MRG(MORF4-related gene)-binding protein;URCC4
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| C20orf20-1315H | Recombinant Human Chromosome 20 0pen Reading Frame 20, His-tagged | E.coli | Human | His |
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| C20ORF20-26614TH | Recombinant Human C20ORF20, His-tagged | E.coli | Human | His | 22-204 a.a. |
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| C20ORF20-26617TH | Recombinant Human C20ORF20, His-tagged | E.coli | Human | His | 204 amino acids |
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| C20orf20-8119HCL | Recombinant Human C20orf20 293 Cell Lysate | HEK293 | Human | Non |
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| C20orf20-301116H | Recombinant Human C20orf20 protein, GST-tagged | E.coli | Human | GST | Met1-Thr204 |
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Involved Pathway
C20orf20 involved in several pathways and played different roles in them. We selected most pathways C20orf20 participated on our site, such as Chromatin modifying enzymes,Chromatin organization,HATs acetylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with C20orf20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| HATs acetylate histones | MBIP,KAT6A,DMAP1,EPC1,EP400,ING5B,MEAF6,MSL1A,CCDC101,TADA2A |
| Chromatin organization | KDM2A,MBD3B,SMARCB1A,KDM1B,RBBP7,ING5A,JADE1,CHD4A,KDM3A,TADA2A |
| Chromatin modifying enzymes | KAT6A,PBRM1,CAPNS2,SMARCC1B,SMARCB1,GATAD2A,SAP18,KANSL3,KDM1A,KDM5A |
Protein Function
C20orf20 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by C20orf20 itself. We selected most functions C20orf20 had, and list some proteins which have the same functions with C20orf20. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | AAGAB,KREMEN1,DHX32,USP44,ABCF1,BMPR1AA,SNX6,NAA35,C11orf46,SNRPA |
Interacting Protein
C20orf20 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C20orf20 here. Most of them are supplied by our site. Hope this information will be useful for your research of C20orf20.
MORF4L2;MORF4L1;ACTL6A
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References
- Ilhan, A; Gartner, W; et al. Localization and characterization of the novel protein encoded by C20orf3. BIOCHEMICAL JOURNAL 414:485-495(2008).
- Alvarez, B; Gomez, N; et al. Molecular cloning characterization and expression of porcine immunoreceptor SIRP alpha. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 31:307-318(2007).
