Recombinant Human CHN1 Protein, MYC/DDK-tagged

• Cat.No.: CHN1-3230H
• Product Overview: Recombinant Human CHN1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: This gene encodes GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. Mutations in this gene are associated with Duane's retraction syndrome 2 (DURS2). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 53 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CHN1 chimerin (chimaerin) 1 [ Homo sapiens ]
• Official Symbol: CHN1
• Synonyms: ARHGAP2; CHN; DURS2; NC; RHOGAP2
• Gene ID: 1123
• mRNA Refseq: NM_001025201
• Protein Refseq: NP_001020372
• MIM: 118423
• UniProt ID: P15882