Recombinant Human CHML, His-tagged

• Cat.No.: CHML-26718TH
• Product Overview: Recombinant full length Human CHML expressed in Saccharomyces cerevisiae with His tag; amino acids 1-656, Predicted MWt 74kDa.

Specification

• Species: Human
• Tag: His
• ProteinLength: 1-656 a.a.
• Description: The product of the CHML gene supports geranylgeranylation of most Rab proteins and may substitute for REP-1 in tissues other than retina. CHML is localized close to the gene for Usher syndrome type II.
• Conjugation: HIS
• Biological activity: Activity:1 pmol of CHML will mediate transfer of 2 pmol of geranylgeraniol by RabGGTase onto 1 pmol of Rab7 in 3 minutes.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 5mM DTT, 40mM Sodium chloride, 25mM HEPES, pH 7.2
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Full Length: Full L.

Gene Information

• Gene Name: CHML choroideremia-like (Rab escort protein 2) [ Homo sapiens ]
• Official Symbol: CHML
• Synonyms: CHML; choroideremia-like (Rab escort protein 2); rab proteins geranylgeranyltransferase component A 2; REP 2
• Gene ID: 1122
• mRNA Refseq: NM_001821
• Protein Refseq: NP_001812
• MIM: 118825
• Uniprot ID: P26374
• Chromosome Location: 1q42-qter
• Function: GTPase activator activity; Rab geranylgeranyltransferase activity