CHML
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Official Full Name
choroideremia-like (Rab escort protein 2) -
Overview
The product of the CHML gene supports geranylgeranylation of most Rab proteins and may substitute for REP-1 in tissues other than retina. CHML is localized close to the gene for Usher syndrome type II. -
Synonyms
CHML;choroideremia-like (Rab escort protein 2);rab proteins geranylgeranyltransferase component A 2;REP 2;CHM like;Choroideraemia like protein;Rab escort protein 2;REP2;OTTHUMP00000037644;REP-2, Rab escort protein 2;choroideraemia-like protein
Recombinant Proteins
- Human
- Mouse
- S.Cerevisiae
- Wheat Germ
- Mammalian Cells
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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CHML-1141H |
Active Recombinant Human Choroideremia-like (Rab Escort Protein 2), His-tagged
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S.Cerevisiae | Human | His |
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CHML-1245H | Recombinant Human CHML Protein, GST-Tagged | Wheat Germ | Human | GST |
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CHML-26718TH | Recombinant Human CHML, His-tagged | Human | His | Full L. 1-656 a.a. |
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CHML-3402M | Recombinant Mouse CHML Protein | Mammalian Cells | Mouse | His |
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CHML-350HCL | Recombinant Human CHML cell lysate | Human | Non |
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CHML-1647M | Recombinant Mouse CHML Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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CHML-1647M-B | Recombinant Mouse CHML Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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CHML-3203HF | Recombinant Full Length Human CHML Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 656 amino acids |
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Involved Pathway
CHML involved in several pathways and played different roles in them. We selected most pathways CHML participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CHML were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Protein Function
CHML has several biochemical functions, for example, GTPase activator activity,Rab GTPase binding,oxidoreductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHML itself. We selected most functions CHML had, and list some proteins which have the same functions with CHML. You can find most of the proteins on our site.
Function | Related Protein |
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oxidoreductase activity | GPX5,HMGCRA,CYP2K19,CYP2C19,MOXD1L,CYP1C1,ALOX5B.3,ADH1,PYROXD2,HSD17B13 |
GTPase activator activity | ELMOD1,ARHGEF6,ASAP3,GRTP1A,RABGAP1,PGAM5,TBC1D16,ARHGAP11A,ARHGDIG,RASA3 |
Rab GTPase binding | ZFP652,SYTL2,STX4A,RAB3GAP1,SGSM2,RGP1,EVI5,RAB11FIP4,TBC1D7,RABGGTA |
Interacting Protein
CHML has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHML here. Most of them are supplied by our site. Hope this information will be useful for your research of CHML.
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References
- Namiki, Y; Endoh, D; et al. Genetic mutation associated with meiotic metaphase-specific apoptosis in MRL/MpJ mice. MOLECULAR REPRODUCTION AND DEVELOPMENT 64:179-188(2003).
- Halford, S; Freedman, MS; et al. Characterization of a novel human opsin gene with wide tissue expression and identification of embedded and flanking genes on chromosome 1q43. GENOMICS 72:203-208(2001).