CHML

  • Official Full Name

    choroideremia-like (Rab escort protein 2)
  • Overview

    The product of the CHML gene supports geranylgeranylation of most Rab proteins and may substitute for REP-1 in tissues other than retina. CHML is localized close to the gene for Usher syndrome type II.
  • Synonyms

    CHML;choroideremia-like (Rab escort protein 2);rab proteins geranylgeranyltransferase component A 2;REP 2;CHM like;Choroideraemia like protein;Rab escort protein 2;REP2;OTTHUMP00000037644;REP-2, Rab escort protein 2;choroideraemia-like protein

Recombinant Proteins

  • Human
  • Mouse
  • S.Cerevisiae
  • Wheat Germ
  • Mammalian Cells
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
CHML-1141H Active Recombinant Human Choroideremia-like (Rab Escort Protein 2), His-tagged S.Cerevisiae Human His
CHML-1245H Recombinant Human CHML Protein, GST-Tagged Wheat Germ Human GST
CHML-26718TH Recombinant Human CHML, His-tagged Human His Full L. 1-656 a.a.
CHML-3402M Recombinant Mouse CHML Protein Mammalian Cells Mouse His
CHML-350HCL Recombinant Human CHML cell lysate Human Non
CHML-1647M Recombinant Mouse CHML Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
CHML-1647M-B Recombinant Mouse CHML Protein Pre-coupled Magnetic Beads HEK293 Mouse
CHML-3203HF Recombinant Full Length Human CHML Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 656 amino acids

    Involved Pathway

    CHML involved in several pathways and played different roles in them. We selected most pathways CHML participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CHML were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    CHML has several biochemical functions, for example, GTPase activator activity,Rab GTPase binding,oxidoreductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHML itself. We selected most functions CHML had, and list some proteins which have the same functions with CHML. You can find most of the proteins on our site.

    Function Related Protein
    oxidoreductase activity GPX5,HMGCRA,CYP2K19,CYP2C19,MOXD1L,CYP1C1,ALOX5B.3,ADH1,PYROXD2,HSD17B13
    GTPase activator activity ELMOD1,ARHGEF6,ASAP3,GRTP1A,RABGAP1,PGAM5,TBC1D16,ARHGAP11A,ARHGDIG,RASA3
    Rab GTPase binding ZFP652,SYTL2,STX4A,RAB3GAP1,SGSM2,RGP1,EVI5,RAB11FIP4,TBC1D7,RABGGTA

    Interacting Protein

    CHML has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHML here. Most of them are supplied by our site. Hope this information will be useful for your research of CHML.

    rpoB

    Resources

    References

    • Namiki, Y; Endoh, D; et al. Genetic mutation associated with meiotic metaphase-specific apoptosis in MRL/MpJ mice. MOLECULAR REPRODUCTION AND DEVELOPMENT 64:179-188(2003).
    • Halford, S; Freedman, MS; et al. Characterization of a novel human opsin gene with wide tissue expression and identification of embedded and flanking genes on chromosome 1q43. GENOMICS 72:203-208(2001).

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