Recombinant Human Chloride Intracellular Channel 3, T7-tagged

• Cat.No.: CLIC3-1532H
• Product Overview: Recombinant human CLIC3 (aa. 1-207) produced inE.coliis a 23.8 kDa protein. It was fused to T7 tag at N-terminus.

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Protein Length: 1-207 a.a.
• Description: Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family.
• Purity: 95%.
• Preparation: 0.1mg/0.096 ml.
• Tested Application: E, WB, MS.
• Buffer: 10 mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3.
• Species Reactivity: n/aH.
• Storage: Store at -70°C with any protein, exposing CLIC3 recombinant protein to repeated freeze/thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Gene Information

• Gene Name: CLIC3 chloride intracellular channel 3 [ Homo sapiens ]
• Synonyms: chloride intracellular channel 3; CLIC3; OTTHUMP00000022630
• Gene ID: 9022
• mRNA Refseq: NM_004669
• Protein Refseq: NP_004660
• MIM: 606533
• UniProt ID: O95833
• Chromosome Location: 9q34.3
• Function: chloride ion binding; protein binding; voltage-gated chloride channel activity; voltage-gated ion channel activity