Recombinant Human Chemokine (C-X-C motif) Ligand 3, His-tagged

• Cat.No.: CXCL3-84H
• Product Overview: Recombinant human CXCL3 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 10.1kDa (94aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: CXCL3/GROg is a smallcytokinebelonging to the CXCchemokinefamily. CXCL3 controlsmigrationandadhesionofmonocytesand mediates it effects on its target cell by interacting with a cell surfacechemokine receptorcalledCXCR2.
• Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MASVVTELRC QCLQTLQGIH LKNIQSVNVR SPGPHCAQTE VIATLKNGKK ACLNPASPMV QKIIEKILNKGSTN.
• Form: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 20% glycerol.
• Purity: > 95% by SDS – PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Endotoxin Level: < 1.0 EU per 1 μg of protein (determined by LAL method).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: CXCL3 chemokine (C-X-C motif) ligand 3
• Synonyms: GRO3; GROg; MIP2B; SCYB3; MIP-2b; CINC-2b; GRO-gamma; GRO-gamma(1-73); MIP2-beta; SCYB3; C-X-C motif chemokine 3; GRO3 oncogene; Growth-regulated protein gamma; MGSA gamma; chemokine (C-X-C motif) ligand 3; melanoma growth stimulatory activity gamma; Macrophage inflammatory protein 2-beta [Precursor]; MIP2B_HUMAN; CXCL3
• Gene ID: 2921
• mRNA Refseq: NM_002090
• Protein Refseq: NP_002081
• MIM: 139111
• UniProt ID: P19876
• Chromosome Location: 4q21
• Pathway: Cytokine-cytokine receptor interaction
• Function: chemokine activity