Active Recombinant Mouse Chemokine (C-X-C motif) Ligand 3, HIgG1 Fc-tagged

• Cat.No.: CXCL3-236H
• Product Overview: The extracellular domain of human CXCL3 (AAH16308.1)(Ala35-Asn107) is fused to the N-terminus of the Fc region of human IgG1 was expressed in CHO celL

Specification

• Description: CXCL3 (chemokine (C-X-C motif) ligand 3) is a protein-coding gene. Diseases associated with CXCL3 include ovarian epithelial cancer, and familial hypercholesterolemia, and among its related super-pathways are MIF Mediated Glucocorticoid Regulation and Chemokine signaling pathway. GO annotations related to this gene include chemokine activity.
• Source: CHO cells
• Species: Human
• Tag: HIgG1 Fc-tagged
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Measured by its ability to induce myeloperoxidase.
• Molecular Mass: 34KDa (monomer)
• AA Sequence: Ala35-Asn107
• Endotoxin: <0.06 eu/μg="" as="" determined="" by="" lal="">
• Purity: >98%, by SDS-PAGE under reducing conditions.
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.
• Protein length: 35-107 a.a.

Gene Information

• Gene Name: CXCL3 chemokine (C-X-C motif) ligand 3 [ Homo sapiens ]
• Official Symbol: CXCL3
• Synonyms: CXCL3; chemokine (C-X-C motif) ligand 3; GRO3, GRO3 oncogene; C-X-C motif chemokine 3; CINC 2b; GROg; MIP 2b; SCYB3; GRO-gamma; MIP2-beta; MGSA gamma; GRO3 oncogene; GRO-gamma(1-73); growth-regulated protein gamma; macrophage inflammatory protein 2-beta; melanoma growth stimulatory activity gamma; GRO3; MIP2B; MIP-2b; CINC-2b
• Gene ID: 2921
• mRNA Refseq: NM_002090
• Protein Refseq: NP_002081
• MIM: 139111
• UniProt ID: P19876
• Chromosome Location: 4q21
• Pathway: Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; G alpha (i) signalling events, organism-specific biosystem
• Function: chemokine activity