Recombinant Human CFHR3 Protein, His-tagged

• Cat.No.: CFHR3-765H
• Product Overview: Recombinant Human CFHR3 Protein (Glu208-Glu330) with His tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 17.7 kDa; Accurate Molecular Mass: 18 kDa
• Protein length: Glu208-Glu330
• Purity: > 97%
• Applications: Cell culture; Activity Assays.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: CFHR3 complement factor H related 3 [ Homo sapiens (human) ]
• Official Symbol: CFHR3
• Synonyms: CFHR3; complement factor H related 3; FHR3; HLF4; CFHL3; FHR-3; DOWN16; complement factor H-related protein 3; H factor-like 4; H factor-like protein 3
• Gene ID: 10878
• mRNA Refseq: NM_021023
• Protein Refseq: NP_066303
• MIM: 605336
• UniProt ID: Q02985