Recombinant Human CFHR3 protein, His & GST-tagged

• Cat.No.: CFHR3-1773H
• Product Overview: Recombinant Human CFHR3 aa. (Gln19~Glu330) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Protein Length: Gln19~Glu330
• Description: The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Form: Freeze-dried powder
• Molecular Mass: 65kDa as determined by SDS-PAGE reducing conditions.
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP; CoIP; Purification; Amine Reactive Labeling.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Concentration: 200μg/mL
• Storage buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
• Isoelectric Point: 7.8

Gene Information

• Gene Name: CFHR3 complement factor H related 3 [ Homo sapiens (human) ]
• Official Symbol: CFHR3
• Synonyms: CFHR3; complement factor H related 3; FHR3; HLF4; CFHL3; FHR-3; DOWN16; complement factor H-related protein 3; H factor-like 4; H factor-like protein 3
• Gene ID: 10878
• mRNA Refseq: NM_001166624.1
• Protein Refseq: NP_001160096.1
• UniProt ID: Q02985