Recombinant Human CENPJ, GST-tagged

Cat.No. : CENPJ-11097H
Product Overview : Recombinant Human CENPJ protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Availability March 15, 2025
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Species : Human
Source : E.coli
Tag : GST
Protein Length : C-term-306a.a.
Description : This gene encodes a component of the chromosomal passenger complex. This complex is an essential regulator of mitosis and cell division. This protein is cell-cycle regulated and is required for chromatin-induced microtubule stabilization and spindle formation. Alternate splicing results in multiple transcript variants. Pseudgenes of this gene are found on chromosomes 7, 8 and 16.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name CENPJ centromere protein J [ Homo sapiens ]
Official Symbol CENPJ
Synonyms CENPJ; centromere protein J; MCPH6, microcephaly, primary autosomal recessive 6; BM032; CPAP; LAP; LIP1; Sas 4; SASS4; SCKL4; LAG-3-associated protein; LYST-interacting protein 1; LYST-interacting protein LIP1; LYST-interacting protein LIP7; centrosomal P4.1-associated protein; MCPH6; Sas-4; CENP-J; MGC131581; MGC131582; MGC142222; MGC142224;
Gene ID 55835
mRNA Refseq NM_018451
Protein Refseq NP_060921
MIM 609279
UniProt ID Q9HC77
Chromosome Location 13q12.12
Pathway Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Centrosome maturation, organism-specific biosystem; G2/M Transition, organism-specific biosystem; Loss of Nlp from mitotic centrosomes, organism-specific biosystem; Loss of proteins required for interphase microtubule organization??from the centrosome, organism-specific biosystem; Mitotic G2-G2/M phases, organism-specific biosystem;
Function protein binding; protein domain specific binding; protein kinase binding; tubulin binding;

Not For Human Consumption!

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