Recombinant Human CDKN2C, GST-tagged
Cat.No. : | CDKN2C-1475H |
Product Overview : | Recombinant full-length human p18INK4C was expressed inE. colicells using an N-terminal GST tag. MW = 42 kDa. |
- Specification
- Gene Information
- Related Products
- Download
Species : | Human |
Source : | E.coli |
Tag : | GST |
Description : | p18INK4C is a member of the INK4 family of proteins that regulate the G1 to S cell cycle transition by binding to and inhibiting the pRb kinase activity of cyclin-dependent kinases 4 and 6. Mutation of p18INK4C impairs B-cell terminal differentiation and confers increased susceptibility to tumor development. p18INK4C can function as a tumor suppressor gene in Hodgkins lymphoma and its inactivation may contribute to the cell cycle deregulation and defective terminal differentiation characteristic of the Reed-Sternberg cells. |
Sequence : | Full-length. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name | CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) [ Homo sapiens ] |
Synonyms | CDKN2C; cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4); p18; INK4C; p18-INK4C; cyclin-dependent kinase inhibitor 2C; CDK6 inhibitor p18; OTTHUMP00000009731; cyclin-dependent inhibitor; cyclin-dependent kinase 4 inhibitor C; cyclin-dependent kinase 6 inhibitor p18; CDKN6; OTTHUMP00000009730; OTTHUMP00000046546; p18-INK4c; p18-INK6; Cyclin-dependent kinase 6 inhibitor |
Gene ID | 1031 |
mRNA Refseq | NM_001262 |
Protein Refseq | NP_001253 |
MIM | 603369 |
UniProt ID | P42773 |
Chromosome Location | 1p32 |
Pathway | Cell cycle |
Function | cyclin-dependent protein kinase inhibitor activity; protein binding; protein kinase binding |
◆ Recombinant Proteins | ||
CDKN2C-1475H | Recombinant Human CDKN2C, GST-tagged | +Inquiry |
CDKN2C-3230HF | Recombinant Full Length Human CDKN2C Protein, GST-tagged | +Inquiry |
CDKN2C-796R | Recombinant Rhesus monkey CDKN2C Protein, His-tagged | +Inquiry |
CDKN2C-117H | Recombinant Human CDKN2C protein, T7-tagged | +Inquiry |
CDKN2C-622R | Recombinant Rhesus Macaque CDKN2C Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
CDKN2C-7612HCL | Recombinant Human CDKN2C 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Ask a Question for All CDKN2C Products
Required fields are marked with *
My Review for All CDKN2C Products
Required fields are marked with *
0
Inquiry Basket