Recombinant Human CDK2AP2, GST-tagged

• Cat.No.: CDK2AP2-11048H
• Product Overview: Recombinant Human CDK2AP2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-126a.a.
• Description: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CDK2AP2 cyclin-dependent kinase 2 associated protein 2 [ Homo sapiens ]
• Official Symbol: CDK2AP2
• Synonyms: CDK2AP2; cyclin-dependent kinase 2 associated protein 2; CDK2 associated protein 2; cyclin-dependent kinase 2-associated protein 2; DOC 1R; p14; tumor suppressor deleted in oral cancer related 1; DOC-1-related protein; CDK2-associated protein 2; tumor suppressor deleted in oral cancer-related 1; DOC-1R; FLJ10636
• Gene ID: 10263
• mRNA Refseq: NM_005851
• Protein Refseq: NP_005842
• UniProt ID: O75956
• Chromosome Location: 11q13