Recombinant Human CDC25C
| Cat.No. : | CDC25C-27900TH |
| Product Overview : | Recombinant full length Human Cdc25C with N-terminal proprietary tag, 84kDa. |
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| Description : | This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. |
| Protein length : | 473 amino acids |
| Molecular Weight : | 84.000kDa inclusive of tags |
| Source : | Baculovirus infected sf9 cells |
| Biological activity : | The Specific activity of CDC25C-27900TH was determined to be 22 nmol/min/mg. |
| Form : | Liquid |
| Purity : | by SDS-PAGE |
| Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5 |
| Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequence Similarities : | Belongs to the MPI phosphatase family.Contains 1 rhodanese domain. |
| Tag : | Non |
| Gene Name | CDC25C cell division cycle 25 homolog C (S. pombe) [ Homo sapiens ] |
| Official Symbol | CDC25C |
| Synonyms | CDC25C; cell division cycle 25 homolog C (S. pombe); CDC25, cell division cycle 25 homolog C (S. cerevisiae) , cell division cycle 25C; M-phase inducer phosphatase 3; PPP1R60; protein phosphatase 1; regulatory subunit 60; |
| Gene ID | 995 |
| mRNA Refseq | NM_001790 |
| Protein Refseq | NP_001781 |
| MIM | 157680 |
| Uniprot ID | P30307 |
| Chromosome Location | 5q31 |
| Pathway | Activation of ATR in response to replication stress, organism-specific biosystem; Cell Cycle Checkpoints, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; |
| Function | WW domain binding; hydrolase activity; protein binding; protein tyrosine phosphatase activity; |
Not For Human Consumption!
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