CDC25C

  • Official Full Name

    cell division cycle 25 homolog C
  • Overview

    M-phase inducer phosphatase 3, also known as CDC25C, is a tyrosine phosphatase expressed predominantly in G2 phase. It directly dephosphorylates CDC2 and triggers entry into mitosis. M-phase inducer phosphatase 3 is also thought to suppress p53-induced gr
  • Synonyms

    CDC25C;cell division cycle 25 homolog C (S. pombe);CDC25, cell division cycle 25 homolog C (S. cerevisiae) , cell division cycle 25C;M-phase inducer phosphatase 3;PPP1R60;protein phosphatase 1;regulatory subunit 60;mitosis inducer CDC25;cell div

Recombinant Proteins

  • Human
  • Mouse
  • E.coli
  • Sf9 Cells
  • Wheat Germ
  • Mammalian Cells
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • Avi
  • Fc
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
CDC25C-11001H Recombinant Human CDC25C, His-tagged E.coli Human His 1-279a.a.
CDC25C-1513H Active Recombinant Human CDC25C, GST-tagged Sf9 Cells Human GST Full length
CDC25C-0918H Recombinant Human CDC25C Protein, GST-Tagged Wheat Germ Human GST
CDC25C-1576H Recombinant Human Cell Division Cycle 25 Homolog C (S. pombe), GST-tagged Sf9 Cells Human GST
CDC25C-27900TH Recombinant Human CDC25C Sf9 Cells Human Non 473 amino acids
CDC25C-3133M Recombinant Mouse CDC25C Protein Mammalian Cells Mouse His
CDC25C-699H Recombinant Human Cell Division Cycle 25 Homolog C (S. Pombe) E.coli Human Non
CDC25C-7664HCL Recombinant Human CDC25C 293 Cell Lysate HEK293 Human Non
CDC25C-1480M Recombinant Mouse CDC25C Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
CDC25C-1480M-B Recombinant Mouse CDC25C Protein Pre-coupled Magnetic Beads HEK293 Mouse
CDC25C-2676H Recombinant Human CDC25C protein, His-tagged E.coli Human His 1-473aa
CDC25C-3054HF Recombinant Full Length Human CDC25C Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 473 amino acids
CDC25C-5300H Recombinant Human CDC25C Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
Cdc25c-853M Recombinant Mouse Cdc25c Protein, MYC/DDK-tagged HEK293 Mouse DDK&Myc

    Involved Pathway

    CDC25C involved in several pathways and played different roles in them. We selected most pathways CDC25C participated on our site, such as Cell cycle,Oocyte meiosis,Progesterone-mediated oocyte maturation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDC25C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Oocyte meiosis CPEB1A,PPP2R5C,MAPK12B,PPP3R2,PRKACBB,ESPL1,PPP2R5CB,ANAPC1,YWHAG1,CALML5
    Progesterone-mediated oocyte maturation ANAPC5,PIK3CB,RPS6KA2,HSP90AA1.2,ADCY1B,HSP90AA1.1,MAPK14B,INS2,AKT2,PGR
    Cell cycle E2F4,BUB1,BORA,USO1,SYCP2,HIST2H3C,MIS18A,KNTC1,NCAPG2,CDC25A
    MicroRNAs in cancer VIM,ERBB2,BCL2L2,TNXB,PRKCB,MDM4,EFNA3,SHC1,TNR,CCND2

    Protein Function

    CDC25C has several biochemical functions, for example, WW domain binding,protein binding,protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDC25C itself. We selected most functions CDC25C had, and list some proteins which have the same functions with CDC25C. You can find most of the proteins on our site.

    Function Related Protein
    protein binding COPS5,PPIB,BCL2L16,SKIL,USP28,DLL1,SYNPO2L,GADD45GIP1,KCNQ4,ELP4
    protein kinase binding RPTOR,IKBKB,CDK5RAP1,LIMS1,KCNQ3,POLA1,MAP2K7,SHC3,ATG13,SCN5A
    WW domain binding FAM189B,TRAF4,DNM2,TCEAL2,PMEPA1,WBP11,TCEAL1,PPARG,TCEAL5,WBP5
    protein tyrosine phosphatase activity RNGTT,TPTE,DUSP16,PTPRJA,PTPN2,CDC14B,DUSP2,CDC14AB,MTMR7B,PTPRG

    Interacting Protein

    CDC25C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDC25C here. Most of them are supplied by our site. Hope this information will be useful for your research of CDC25C.

    PLK1;CHEK1;CDK1;LZTS1;Cdk1;YWHAZ;PPP2R5D;EGFR;YWHAB;YWHAE

    Resources

    References

    • Porcu, E; Viola, G; et al. TR-644 a novel potent tubulin binding agent induces impairment of endothelial cells function and inhibits angiogenesis. ANGIOGENESIS 16:647-662(2013).
    • Chang, MC; Tsai, YL; et al. Butyrate induces reactive oxygen species production and affects cell cycle progression in human gingival fibroblasts. JOURNAL OF PERIODONTAL RESEARCH 48:66-73(2013).

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